Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

HqO

Real Estate

HqO

HqO is transforming how people connect with each other and the places they work. The HqO Workplace Experience Platform makes it easy for companies and commercial property teams to create modern workplaces through world-class amenities and services that allow people to thrive and do their best work. Active in over 200 million square feet in 25 countries, 57% of the Fortune 100 rely on HqO to enhance their workplace experiences, improve employee satisfaction, and drive operational excellence.

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Dust Identity

Software

Cybersecurity

Nanotechnology

Dust Identity

DUST Identity is the creator of the Diamond Unclonable Security Tag (DUST), a technology utilizing microscopic engineered diamonds to create an unclonable identity layer on any object. At DUST Identity, we believe that authentic products tell powerful stories and build beloved brands. Our customers come to us in search of advanced identity tools to protect and connect the most valuable products and physical objects from battlefields to playing fields and everything in between. We deliver elegant, adaptable, long-lasting solutions that solve our customers' need for more control over their brands, products, and parts. DUST Identity, established in 2018 and headquartered in Boston, was created by a team of quantum physics, nanotechnology, and cyber security experts. The company is an MIT spinoff, has participated in several DARPA programs, and is backed by Castle Island Ventures, Kleiner Perkins, Lockheed Martin Ventures, Airbus Ventures, Highland Capital Partners, New Science Ventures, 8VC, Angular Ventures, and others.

Reprise

Software

Reprise

Reprise empowers enterprise sales and marketing teams to build personalized, interactive demos that lead to greater conversions, shorter sales cycles, and more revenue. For sales and marketing leaders who strive to expertly showcase their products, Reprise is the only enterprise-class demo creation platform that fully integrates live demos, guided demos, and product tours to seamlessly show the value of your product at every phase of the buyer's journey. Launched in 2020, Reprise has been recognized as a leader in G2's winter 2023 report of best Mid-Market Content Experience Platforms. Backed by ICONIQ Growth, Bain Capital Ventures, Accomplice VC, and Glasswing Ventures, Reprise is changing how companies deliver demos.

Scipher Medicine

Healthcare

Scipher Medicine

Scipher Medicine is building the future of patient treatment. Most patients who are prescribed blockbuster therapies today don’t respond to the treatment, costing the healthcare industry billions in wasted drugs while patients continue to suffer. Scipher's platform identifies which drug will work based on the patient's fundamental disease biology and not based on symptoms, disease classification, or medical bias. A simple test predicts which drug he/she will respond to, ensuring that the most optimal treatment is prescribed from day one. The molecular data generated by our tests is then used to fuel novel target discovery to address a clear unmet medical need in patients who do not respond to any existing therapy.

Rezonate

Software

Rezonate

Rezonate.io is a cutting-edge Identity Centric Security Platform designed to fortify both human and machine identities against cyber threats throughout their entire access journey to business assets. With a bold proclamation that "A/B Testing is Dead," Rezonate.io champions a shift from traditional methods to AI-driven solutions. Their platform offers comprehensive features such as real-time monitoring of privileges and activities, risk reduction, and active threat mitigation. Recognized as a "Cool Vendor" in the 2023 Gartner® Cool Vendors™ in Identity-First Security report, Rezonate.io is committed to delivering an all-encompassing identity-first security platform that bolsters security posture, fortifies defense mechanisms, and facilitates effective threat remediation. Rezonate.io's platform is uniquely designed to discover, profile, and protect identities, ensuring secure access to cloud infrastructure and critical SaaS applications. It provides continuous exposure reduction by uncovering and rectifying weak authentication, misconfigured trust relations, and other vulnerabilities. Moreover, the platform's adaptive access engine optimizes security controls, ensuring that identities are managed efficiently.

Piaggio Fast Forward

Automotive

Piaggio Fast Forward

Piaggio Fast Forward is a new technology and design company established in 2015 by the Piaggio Group, the manufacturers of Vespa, Aprilia, Moto Guzzi, Derbi, and Gilera. PFF was established with an open mandate to re-think smart mobility platforms in a world where city navigation and short-distance transportation are rapidly changing. We’re a highly creative, motivated, interdisciplinary team of innovators committed to building lightweight, semi-autonomous, and entirely self-driving mobility platforms that easily, safely, and efficiently move people and goods in urban settings

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.