Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Overjet

Overjet is pioneering the next era of dentistry. Modern DSOs and insurance companies are realizing the clinical and operational value of innovative technologies and moving towards smart operations that leverage artificial intelligence. Guided by a patient-centric AI, Overjet’s FDA-cleared platform offers more data points in x-rays than previously possible. It integrates with major practice management and imaging systems to guide clinicians to arrive at precise & accurate diagnostic decisions, better care and patient outcomes that drive dentistry forward. With data-driven diagnoses being the key to success, Overjet enables clinicians to achieve higher clinical accuracy, precision, and consistency. When dentists see objective confirmation of a diagnosis they made, they feel more confident, and patients know they can trust their doctors. Building on formative experiences with MIT and Harvard School of Dental Medicine, Overjet was founded on the vision to enhance clinical decision-making to improve oral health. Every day, some of the largest DSOs, dental groups, and insurance companies rely on accurate information provided by Overjet to deliver care and services.

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Activ Surgical

Healthcare

Activ Surgical

Activ Surgical is a digital surgery pioneer, envisioning a future of collaborative surgery, with surgical intelligence empowering scopes and robots to see what humans cannot see. The top surgeons in the world cannot be everywhere, but with Activ Surgical, their data and insights can be. Founded in 2017, Activ Surgical completed the world ￃﾢ￢ﾂﾬ￢ﾄﾢs first autonomous robotic surgery of soft tissue and is building hardware-agnostic surgical software that allows surgical systems to collaborate with surgeons.

Mainstay

At Mainstay, we believe one conversation can spark a brighter future. Our Engagement Platform makes it easy for colleges and businesses to start and measure conversations that drive action at scale. From our rigorous research methods to our Behavioral Intelligence framework — everything we do is designed to help people take the next step toward achieving their goals.

Provengo

SaaS

Software Development

Provengo

We develop tools for system specification, validation, and correct-by-construction workflow automation, based on groundbreaking - yet friendly - formal methods.

Codametrix

Software

Healthcare

Codametrix

CodaMetrix is at the forefront of revolutionizing the medical coding industry through its AI-driven solutions. As a recognized leader, we proudly hold the No. 1 position in the “Reduce Cost of Care” category in the 2023 KLAS Emerging Solutions Report. Our flagship platform, CMX, is a multi-specialty coding AI-platform designed to seamlessly translate clinical information into precise medical codes, catering to both fee-for-service and value-based care models.

ChaosSearch

Software

ChaosSearch

ChaosSearch enables customers to Know Better, delivering data insights at scale while achieving the true promise of data lake economics. The ChaosSearch Data Platform connects to and indexes data within a customer’s cloud storage environment, rendering it fully searchable and available for analysis with existing data tools – all with unlimited scale, industry-leading resiliency, and massive cost savings.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.