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Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Boston startups

Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

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Reprise

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Software iconSoftware

Reprise empowers enterprise sales and marketing teams to build personalized, interactive demos that lead to greater conversions, shorter sales cycles, and more revenue. For sales and marketing leaders who strive to expertly showcase their products, Reprise is the only enterprise-class demo creation platform that fully integrates live demos, guided demos, and product tours to seamlessly show the value of your product at every phase of the buyer's journey. Launched in 2020, Reprise has been recognized as a leader in G2's winter 2023 report of best Mid-Market Content Experience Platforms. Backed by ICONIQ Growth, Bain Capital Ventures, Accomplice VC, and Glasswing Ventures, Reprise is changing how companies deliver demos.

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Iterative Health

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Iterative Health is pioneering the use of artificial intelligence-based precision medicine in gastroenterology (GI), with the aim of helping to optimize clinical trials investigating treatment of inflammatory bowel disease (IBD). We use advanced machine learning and computer vision to interpret endoscopic images along with other types of data, helping clinicians to better assess patients with potential GI problems. This gives practitioners enhanced capabilities in the detection, annotation, disease scoring and treatment of GI related diseases. Iterative Health is initially applying these advances towards standardizing disease severity characterization for inflammatory bowel disease. Ultimately, the company aims to establish more meaningful endpoints to serve as better predictors of both therapeutic response and disease outcomes. The company is headquartered in Cambridge, Massachusetts.

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Legacy

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Legacy is the fatherhood company. We are building a full suite of solutions and services for future, expecting, and new fathers. Our first product allows men to test and freeze their sperm without ever visiting a clinic. We are a Harvard incubated company that went through Y Combinator in the Summer '19 Batch and won TechCrunch's disrupt in Berlin last November. 

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Entrada Therapeutics

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Biotech iconBiotech

Headquartered in Boston’s Seaport community, Entrada Therapeutics is a growing biopharmaceutical company innovating to transform the treatment of devastating diseases through intracellular therapeutics. We’re establishing a new class of medicines, Endosomal Escape Vehicles (EEV™), with the potential to engage intracellular targets that have long been considered inaccessible and undruggable. Our EEV™ therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues with an improved therapeutic index.

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Tomorrow.io

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Climate Tech iconClimate Tech

Tomorrow.io is the world’s leading Weather and Climate Security Platform, equipping humanity with the weather intelligence needed to thrive and adapt in an era of climate crisis. Through predictive and actionable insights, teams adapt to any weather-related challenge at scale, both in real-time and in advance of business impact. Customers, including Uber, Delta, National Grid, and more, use Tomorrow.io to significantly improve operational efficiency, automate risk management, and customize resiliency plans to meet sustainability goals.

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Paperless Parts Inc

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Manufacturing iconManufacturing

Paperless Parts is a Boston-based Series B SaaS company backed by OpenView leading the digital transformation for custom part manufacturers. Our cloud-based software helps manufacturers increase revenue and win more business. Paperless Parts' patented technology and proprietary geometry engine unlock hidden insights that enable job shop manufacturers to modernize and grow their businesses. Paperless Parts integrates with your ERP system to level up how you quote and communicate with customers by rapidly pinpointing manufacturability issues, creating quotes, and processing orders for additive manufacturing, sheet metal fabrication, and CNC machining production processes.

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