Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

Join Discover

Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Emulate

Healthcare

Emulate

Emulate Inc. is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health. Our lab-ready Human Emulation System® includes three components: Zoë® Culture Module, Organ-Chips, and analytical software applications. The platform provides a window into the inner workings of human biology and disease—offering researchers a new technology designed to predict human response with greater precision and detail than conventional cell culture or animal-based experimental testing. Research conducted using our Organ-Chips has been published in high-impact scientific journals, including Science. In addition, Organ-Chips have been acquired by the Museum of Modern Art (MoMA) in New York for their permanent collection and have also been awarded Product Design of the Year 2015 by London’s Design Museum.

Details

Sense Energy

Electronics

Sense Energy

Sense's mission is to make all homes intelligent by keeping people informed about what's happening in their homes and helping to make them safer, more efficient, and more reliable. Sense was born from the simple idea that people should know what's happening in their homes. We track calories, footsteps, mpg's yet we know so little about the place where we spend so much time. Energy efficiency and home automation begin with information. We built the Sense home energy monitor to provide people with information about their homes in the simplest, most helpful way possible.

BlockJoy

Blockchain

BlockJoy

BlockJoy allows you to deploy and run your own blockchain nodes on any infrastructure you choose. It started as a project to manager staking with friends and family. We built advanced tooling to optimize validator management for teams of two. But, due to the sheer difficulty of installing and running nodes, our little VaaS company grew crazy fast. We quickly realized that VaaS can’t work for a network because it centralizes control. We turned our platform into a SaaS tool so that anyone could launch and run their own node with full control over where and on what infrastructure it runs. Now, network operators can run their own nodes; BlockJoy just takes the headaches away.

Reprise

Software

Reprise

Reprise empowers enterprise sales and marketing teams to build personalized, interactive demos that lead to greater conversions, shorter sales cycles, and more revenue. For sales and marketing leaders who strive to expertly showcase their products, Reprise is the only enterprise-class demo creation platform that fully integrates live demos, guided demos, and product tours to seamlessly show the value of your product at every phase of the buyer's journey. Launched in 2020, Reprise has been recognized as a leader in G2's winter 2023 report of best Mid-Market Content Experience Platforms. Backed by ICONIQ Growth, Bain Capital Ventures, Accomplice VC, and Glasswing Ventures, Reprise is changing how companies deliver demos.

Spoiler Alert

Software

Spoiler Alert

Transforming excess inventory from a problem into a profit. Spoiler Alert is a B2B sales software company helping CPG manufacturers and distributors to manage excess and slow-moving inventory by digitizing the liquidation process. Our goal is to help our customers recover value for products that otherwise would be wasted, allowing them to increase profits, strengthen customer relationships, increase the effectiveness of supply chain managers, and allow for more accurate demand planning. Founded by alumni of MIT, Spoiler Alert works with some of the world's largest companies, including Campbell Soup Company, Danone North America, HelloFresh, KeHE Distributors, Kraft Heinz, Mondelēz, Johnsonville, and Nestlé, along with a growing network of discount channels committed to increasing affordable food access.

FreezeNit

Healthcare

FreezeNit

FreezeNit will improve the treatment of head lice for millions of families in the US. Our innovative approach simultaneously freezes and asphyxiates lice using only cold CO2 gas, in one short, non-toxic treatment.

Details

Go to Directory

Latest News

Dive into our blog for the latest trends and success stories from the Boston's startup community.

July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.