Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Scipher Medicine

Healthcare

Scipher Medicine

Scipher Medicine is building the future of patient treatment. Most patients who are prescribed blockbuster therapies today don’t respond to the treatment, costing the healthcare industry billions in wasted drugs while patients continue to suffer. Scipher's platform identifies which drug will work based on the patient's fundamental disease biology and not based on symptoms, disease classification, or medical bias. A simple test predicts which drug he/she will respond to, ensuring that the most optimal treatment is prescribed from day one. The molecular data generated by our tests is then used to fuel novel target discovery to address a clear unmet medical need in patients who do not respond to any existing therapy.

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Gradient AI

Insurtech

Gradient AI

Gradient AI was founded in order to address the need for state-of-the-art Artificial Intelligence (AI) and Machine Learning (ML) solutions for the trillion-dollar insurance industry. Our software-as-a-service platform uses AI to help commercial insurers automate and improve underwriting results, reduce claim costs, and improve operational efficiencies. Our software and models are utilized by many of the world’s most recognized Insurance Carriers, MGAs, TPAs, Pools, PEOs and more. Our team of expert Data Scientists and Insurance Technology experts have an exceptional history of building wildly successful insurance technology companies, with the most satisfied customers in the industry. At GradientAI we focus exclusively on delivering measurable results for your underwriting and claims operations.

Goldcast

Event Tech

Goldcast

Goldcast is a tailored B2B Events Platform that transforms marketing through the effortless hosting of engaging digital and in-person events. Thousands of enterprise B2B marketers, from companies like Adobe, Microsoft, Zuora, and Mailchimp, leverage Goldcast to boost attendance, create captivating experiences, repurpose event content, and capitalize on intent data. Elevate your events with Goldcast for true audience engagement, brand development, and revenue growth; moving beyond basic events to revenue-driving engagement from webinars and product demos to thought leadership panels and in-person dinners.

Soofa

Software

Soofa

Founded in 2014 out of the MIT media lab, sustainable Soofa Signs are the leading solar-powered communication tool for cities and advertisers. Currently, Soofa Signs has homes in over 57 cities across the U.S. with plans to expand. Soofa advertisers are guaranteed high traffic, unique locations, countless ways to measure success, and a platform to update messaging in real time. We’ve worked with brands large and small like Harpoon, RedBull, New England Revolution, and Wayfair, proving that more businesses are emphasizing sustainable advertising practices. Additionally, cities like Boston, Atlanta, and Miami utilize Soofa Signs to create unique and engaging messaging with their communities thanks to our neighborhood news feed. If it’s an urgent message, or one just for fun, Soofa Signs make it easy to get information to your intended audience.

Ori

Real Estate

Interior Design

Ori

Ori is a smart space company that empowers people to get the most out of their living areas through the design of multi-functional, robotic-powered interior solutions. We partner with real estate developers, builders, property managers, and architects to optimize the square footage of the built environments they shape in order to create urbanhousing and spaces that are flexible, intelligent, sustainable and affordable. We believe we should expect more from our spaces.

Zus Health

Healthcare

Zus Health

Zus is the only shared health data platform designed to accelerate healthcare data interoperability by providing easy-to-use patient data at the point of care via API, embedded components, and direct EHR integrations. Our mission is to catalyze healthcare's greatest inventors by maximizing the value of patient insights - so that they can build up, not around.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.