Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Zenyai

Software

SaaS

Digital Health

Zenyai

We turn emotions into sounds to help non-verbal and autistic children find their voice and express themselves.

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Zus Health

Healthcare

Zus Health

Zus is the only shared health data platform designed to accelerate healthcare data interoperability by providing easy-to-use patient data at the point of care via API, embedded components, and direct EHR integrations. Our mission is to catalyze healthcare's greatest inventors by maximizing the value of patient insights - so that they can build up, not around.

Emulate

Healthcare

Emulate

Emulate Inc. is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health. Our lab-ready Human Emulation System® includes three components: Zoë® Culture Module, Organ-Chips, and analytical software applications. The platform provides a window into the inner workings of human biology and disease—offering researchers a new technology designed to predict human response with greater precision and detail than conventional cell culture or animal-based experimental testing. Research conducted using our Organ-Chips has been published in high-impact scientific journals, including Science. In addition, Organ-Chips have been acquired by the Museum of Modern Art (MoMA) in New York for their permanent collection and have also been awarded Product Design of the Year 2015 by London’s Design Museum.

Silvertree

Consumer

Silvertree

Silvertree is on a mission to inspire the world’s aging population. We are developing a wellness wearable platform that provides the right balance of safety, connection, and style for active older adults. Aging is a personal experience, yet aging with dignity and independence so often includes the caring involvement of family and loved ones. That is why we are designing a stylish, wrist-worn wearable that is built for safety and deeply rooted in human connection, across generations. We aim to be the consumer brand associated with vitality, style, and independence for the growing population of fifty-five million Americans ages sixty-five and beyond.

Tomorrow.io

Software

Climate Tech

Tomorrow.io

Tomorrow.io is the world’s leading Weather and Climate Security Platform, equipping humanity with the weather intelligence needed to thrive and adapt in an era of climate crisis. Through predictive and actionable insights, teams adapt to any weather-related challenge at scale, both in real-time and in advance of business impact. Customers, including Uber, Delta, National Grid, and more, use Tomorrow.io to significantly improve operational efficiency, automate risk management, and customize resiliency plans to meet sustainability goals.

Soofa

Software

Soofa

Founded in 2014 out of the MIT media lab, sustainable Soofa Signs are the leading solar-powered communication tool for cities and advertisers. Currently, Soofa Signs has homes in over 57 cities across the U.S. with plans to expand. Soofa advertisers are guaranteed high traffic, unique locations, countless ways to measure success, and a platform to update messaging in real time. We’ve worked with brands large and small like Harpoon, RedBull, New England Revolution, and Wayfair, proving that more businesses are emphasizing sustainable advertising practices. Additionally, cities like Boston, Atlanta, and Miami utilize Soofa Signs to create unique and engaging messaging with their communities thanks to our neighborhood news feed. If it’s an urgent message, or one just for fun, Soofa Signs make it easy to get information to your intended audience.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.