Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

Legacy

Healthcare

Legacy

Legacy is the fatherhood company. We are building a full suite of solutions and services for future, expecting, and new fathers. Our first product allows men to test and freeze their sperm without ever visiting a clinic. We are a Harvard incubated company that went through Y Combinator in the Summer '19 Batch and won TechCrunch's disrupt in Berlin last November.

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Emulate

Healthcare

Emulate

Emulate Inc. is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health. Our lab-ready Human Emulation System® includes three components: Zoë® Culture Module, Organ-Chips, and analytical software applications. The platform provides a window into the inner workings of human biology and disease—offering researchers a new technology designed to predict human response with greater precision and detail than conventional cell culture or animal-based experimental testing. Research conducted using our Organ-Chips has been published in high-impact scientific journals, including Science. In addition, Organ-Chips have been acquired by the Museum of Modern Art (MoMA) in New York for their permanent collection and have also been awarded Product Design of the Year 2015 by London’s Design Museum.

Scipher Medicine

Healthcare

Scipher Medicine

Scipher Medicine is building the future of patient treatment. Most patients who are prescribed blockbuster therapies today don’t respond to the treatment, costing the healthcare industry billions in wasted drugs while patients continue to suffer. Scipher's platform identifies which drug will work based on the patient's fundamental disease biology and not based on symptoms, disease classification, or medical bias. A simple test predicts which drug he/she will respond to, ensuring that the most optimal treatment is prescribed from day one. The molecular data generated by our tests is then used to fuel novel target discovery to address a clear unmet medical need in patients who do not respond to any existing therapy.

Activ Surgical

Healthcare

Activ Surgical

Activ Surgical is a digital surgery pioneer, envisioning a future of collaborative surgery, with surgical intelligence empowering scopes and robots to see what humans cannot see. The top surgeons in the world cannot be everywhere, but with Activ Surgical, their data and insights can be. Founded in 2017, Activ Surgical completed the world ￃﾢ￢ﾂﾬ￢ﾄﾢs first autonomous robotic surgery of soft tissue and is building hardware-agnostic surgical software that allows surgical systems to collaborate with surgeons.

Dispense

eCommerce

Dispense

Dispensaries know their customers better than anyone. Dispensary software should give them the flexibility and control needed to make the right decisions and offer exceptional service. Dispense provides cannabis businesses with simple-to-use tools to boost sales and manage operations - on your own terms. The eCommerce software empowers dispensaries to sell online, increase traffic, build customer relationships, and scale businesses. And with our customizable dispensary management functionality, everything integrates easily into your specific operation. Dispense is not a marketplace; you always own your data, so your efforts never benefit your competitors. That means better customer relationships and more online visibility.

Codametrix

Software

Healthcare

Codametrix

CodaMetrix is at the forefront of revolutionizing the medical coding industry through its AI-driven solutions. As a recognized leader, we proudly hold the No. 1 position in the “Reduce Cost of Care” category in the 2023 KLAS Emerging Solutions Report. Our flagship platform, CMX, is a multi-specialty coding AI-platform designed to seamlessly translate clinical information into precise medical codes, catering to both fee-for-service and value-based care models.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.