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Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Boston startups

Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

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Emulate

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Healthcare iconHealthcare

Emulate Inc. is a privately held company that creates advanced in vitro models for understanding how diseases, medicines, chemicals, and foods affect human health. Our lab-ready Human Emulation System® includes three components: Zoë® Culture Module, Organ-Chips, and analytical software applications. The platform provides a window into the inner workings of human biology and disease—offering researchers a new technology designed to predict human response with greater precision and detail than conventional cell culture or animal-based experimental testing. Research conducted using our Organ-Chips has been published in high-impact scientific journals, including Science. In addition, Organ-Chips have been acquired by the Museum of Modern Art (MoMA) in New York for their permanent collection and have also been awarded Product Design of the Year 2015 by London’s Design Museum.

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Guidesly

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Consumer iconConsumer

Experience the great outdoors with Guidesly - the next-generation marketplace that connects you with expert guides for a variety of outdoor activities, from fishing and hunting to ATV/UTV and more. Our website and app (Guidesly Trips) make it easy for you to compare and book trusted guides and discover the perfect adventure tailored to your interests and skill level. Leave the planning to us and trust our experienced guides to lead the way. Guidesly also supports guides by providing innovative solutions to common challenges faced in the outdoor guiding business. Our platform offers powerful tools for guides to manage their businesses more efficiently and effectively so they can focus on what matters most - delivering unforgettable experiences to their guests. Join our community of passionate outdoor enthusiasts and start your next adventure with Guidesly.

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Paperless Parts Inc

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Manufacturing iconManufacturing

Paperless Parts is a Boston-based Series B SaaS company backed by OpenView leading the digital transformation for custom part manufacturers. Our cloud-based software helps manufacturers increase revenue and win more business. Paperless Parts' patented technology and proprietary geometry engine unlock hidden insights that enable job shop manufacturers to modernize and grow their businesses. Paperless Parts integrates with your ERP system to level up how you quote and communicate with customers by rapidly pinpointing manufacturability issues, creating quotes, and processing orders for additive manufacturing, sheet metal fabrication, and CNC machining production processes.

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Linus Health

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Healthcare iconHealthcare

Linus Health is a Boston-based digital health company focused on transforming brain health for people across the world. By advancing how we detect and address cognitive and brain disorders – leveraging cutting-edge neuroscience, clinical expertise, and artificial intelligence – our goal is to enable a future where people can live longer, happier, and healthier lives with better brain health. Our digital platform delivers a proven, practical means of enabling early detection; empowers providers with actionable clinical insights and recommendations; and supports individuals with personalized action plans. We are proud to support leading research institutions, life sciences companies, and healthcare delivery organizations.

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Silvertree

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Consumer iconConsumer

Silvertree is on a mission to inspire the world’s aging population. We are developing a wellness wearable platform that provides the right balance of safety, connection, and style for active older adults. Aging is a personal experience, yet aging with dignity and independence so often includes the caring involvement of family and loved ones. That is why we are designing a stylish, wrist-worn wearable that is built for safety and deeply rooted in human connection, across generations. We aim to be the consumer brand associated with vitality, style, and independence for the growing population of fifty-five million Americans ages sixty-five and beyond.

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Entrada Therapeutics

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Biotech iconBiotech

Headquartered in Boston’s Seaport community, Entrada Therapeutics is a growing biopharmaceutical company innovating to transform the treatment of devastating diseases through intracellular therapeutics. We’re establishing a new class of medicines, Endosomal Escape Vehicles (EEV™), with the potential to engage intracellular targets that have long been considered inaccessible and undruggable. Our EEV™ therapeutics are designed to enable the efficient intracellular delivery of a wide range of therapeutics into a variety of organs and tissues with an improved therapeutic index.

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