Boston Startup Hub

Welcome to the hub for the most groundbreaking and ambitious startups in Boston! Our directory has just landed, want to join us on this exciting journey?

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Featured Startups

Dive into our directory to uncover more innovations that are shaping the city's future.

BIY China

Software

Education

BIY China

Build-It-Yourself offers an art and engineering program driven by technology-in-education research at MIT. Our mission is to inspire and guide the next generation of builders to use technology creatively in a unique global laboratory.

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1upHealth

Healthcare

1upHealth

1upHealth provides the healthcare industry’s most sophisticated FHIR-enabled health data platform for claims and clinical data acquisition, exchange, and compute. From leading health plans and state Medicaid agencies to innovative digital health organizations and top performing ACOs, over 75 health organizations rely on 1upHealth to meet evolving regulatory requirements and optimize claims and clinical data-driven initiatives. With the push towards digital quality measures, population health analytics, value-based contracts, and better healthcare experiences, the 1up managed platform helps our customers to meet the growing demands for data access and connectivity.

Soofa

Software

Soofa

Founded in 2014 out of the MIT media lab, sustainable Soofa Signs are the leading solar-powered communication tool for cities and advertisers. Currently, Soofa Signs has homes in over 57 cities across the U.S. with plans to expand. Soofa advertisers are guaranteed high traffic, unique locations, countless ways to measure success, and a platform to update messaging in real time. We’ve worked with brands large and small like Harpoon, RedBull, New England Revolution, and Wayfair, proving that more businesses are emphasizing sustainable advertising practices. Additionally, cities like Boston, Atlanta, and Miami utilize Soofa Signs to create unique and engaging messaging with their communities thanks to our neighborhood news feed. If it’s an urgent message, or one just for fun, Soofa Signs make it easy to get information to your intended audience.

Zus Health

Healthcare

Zus Health

Zus is the only shared health data platform designed to accelerate healthcare data interoperability by providing easy-to-use patient data at the point of care via API, embedded components, and direct EHR integrations. Our mission is to catalyze healthcare's greatest inventors by maximizing the value of patient insights - so that they can build up, not around.

Spoiler Alert

Software

Spoiler Alert

Transforming excess inventory from a problem into a profit. Spoiler Alert is a B2B sales software company helping CPG manufacturers and distributors to manage excess and slow-moving inventory by digitizing the liquidation process. Our goal is to help our customers recover value for products that otherwise would be wasted, allowing them to increase profits, strengthen customer relationships, increase the effectiveness of supply chain managers, and allow for more accurate demand planning. Founded by alumni of MIT, Spoiler Alert works with some of the world's largest companies, including Campbell Soup Company, Danone North America, HelloFresh, KeHE Distributors, Kraft Heinz, Mondelēz, Johnsonville, and Nestlé, along with a growing network of discount channels committed to increasing affordable food access.

Flipside Crypto

FinTech

Flipside Crypto

Flipside enables blockchains to live up to their full potential, by decoding and explaining blockchain behaviors. Our proprietary process extracts all of the data from blockchains and applies labels to transactions in order to identify and understand on-chain behaviors. The data is then streamed into our Business Intelligence Dashboards, to provide a clear view of real-time stakeholder behaviors and all asset flows. Flipside provides analytics to more than 80 cryptocurrency organizations and distributes ratings products via partners such as CoinMarketCap, Messari, MarketWatch and TheStreet. Flipside Crypto is backed by True Ventures, Founder Collective, CoinBase Ventures, Digital Currency Group, Galaxy Digital, and other investors.

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Latest News

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July 22nd, 2025

Boston Tech Talks: Arnar Larusson from Tyme Wear

In this edition of Boston Tech Talks, Arnar Larusson, co-founder of Tyme Wear, shares how his background in biomechanics and engineering led to building a wearable tech startup—and why Boston’s unique mix of resources, talent, and community made it the ideal place to launch.